Als progression reddit

It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time. state farm insurance agents near me Amyotrophic lateral sclerosis (a-my-o-TROE-fik LAT-ur-ul skluh-ROE-sis), or ALS, is a progressive nervous system disease that affects nerve cells in the brain and spinal cord, causing loss of muscle control. ALS is often called Lou Gehrig's disease, after the baseball player who was diagnosed with it. Doctors usually don't know why ALS occurs.It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time.The ALS forum is a support group to help people deal with the daily living issues associated with ALS. The ALS forum will connect you with people that can provide answers, support and help with ALS. We invite you to join our community. Hospices Across the Globe To add a hospice to our listings please use the following form: Add a HospiceWe conclude that the RF Model delivers superior predictions of ALS disease progression. Introduction Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neuron populations of the cerebral cortex, brainstem, and spinal cord, leading to progressive disability and death from respiratory failure. do do do do dodododo 19 ago 2020 ... ALS Progression. My husband was diagnosed with ALS June 2019. It started in his legs and has worked its way up to his limbs and is now ... colonial village apartments Most social media platforms have built-in data analytics tools, enabling companies to track the progress, success. InstBlast is one of those platforms where you can easily get genuine likes for TikTok for free.However, noticing the so-called dents, indentations or grooves far more likely reflects a new awareness of your body’s natural and harmless asymmetry, rather than ALS. “ALS is a …Dec 5, 2022 · ALS is a progressive condition that is terminal within five years for 80% of the people impacted by it. ALS affects the nerves that control movement. As it progresses, people with ALS are unable to move their arms and legs to walk or get out of bed, and they eventually lose the ability to talk, eat, and breathe on their own. 3 How ALS Causes Death 5 dpo symptoms success stories forumIt seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time.Amyotrophic lateral sclerosis (ALS) more commonly referred to as Lou Gehrig’s disease, is a progressive and deadly disease. Many with ALS experience grief and many families of those affected endure the same. At present medical science has demonstrated great potential in finding a workable cure or efficacious therapy. ogletree deakins chambers associate Adf [email protected] is on Instagram • 74. Simplify agile project processes and sprint plans with Asana. Java(sprint boot), Spark, Scala/Python, ADF, ADB, SQL, AWS Lambda, Kinesis Streaming 2.This is the fastest progression of a case of ALS I have ever heard of. Has anyone else ever seen things go downhill so quickly? Everyone is in shock. 14 9 9 comments Best Add a Comment ROARscaredyoudidntI • 4 yr. ago I worked with a man that was stable one week and gone the next. It can drag out or be so fast you're not even expecting it.Background: In a Phase 3 study, amyotrophic lateral sclerosis (ALS) patients experienced significantly less physical functional decline with 24-week edaravone vs placebo, followed by …als als? atrophy back breathing breathing problems bulbar bulbar als death eating hyperreflexia muscles problems progression speech swallowing symptoms tongue tongue atrophy twitches twitching weakness Not open for further replies. 1 2 3 Next S Searcher Active member Joined Oct 17, 2008 Messages 68 Reason Learn about ALS Country US State MD CityJun 29, 2021 · 29 Jun Amyotrophic lateral sclerosis (ALS) is a progressive nervous system disease that affects the nerve cells in the spinal cord and brain, causing the loss of muscle control. The disease primarily affects the muscle, which will ultimately lead to the inability to move later on. george archos salary When my husband Tom was diagnosed with ALS, we were embraced by the ALS community. But as his health declined, I didn't really feel ALS was what was stealing my husband from me. ... See the ALS Ice Bucket Challenge progress! ©2023 All content and works posted on this website are owned and copyrighted by The ALS Association. Lou Gehrig® used ...als als? atrophy back breathing breathing problems bulbar bulbar als death eating hyperreflexia muscles problems progression speech swallowing symptoms tongue tongue atrophy twitches twitching weakness Not open for further replies. 1 2 3 Next S Searcher Active member Joined Oct 17, 2008 Messages 68 Reason Learn about ALS Country US State MD CityAmyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. Although ALS is incurable and fatal, with median survival of 3 years, treatment can... 1955 chevy project car for sale in texas Amyotrophic lateral sclerosis (ALS), which is often called to as “Lou Gehrig’s Disease” in the Americas, is a progressive nervous system degenerating disease that affects nerve cells in the brain and in the spinal column. Motor neurons go from the brain to the spinal cord and to the muscles scattered throughout the body.Most people with ALS eventually lose the ability to walk, dress, write, speak, swallow and breathe, and their life span is shortened. Early symptoms of ALS often include muscle weakness or stiffness. Progression of weakness, wasting and paralysis of the muscles of the limbs, trunk, and those that control vital functions generally follows. antiques craigslist May 24, 2020 #1 Hi, My dad has ALS, and started to show symptoms of ALS a year ago. January 2019 - First he had difficulty with his voice and talking and had muscle …Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motor neurons. Recent studies have implicated that chronic hypoxia and insufficient vascular endothelial growth factor (VEGF)-dependent neuroprotection may lead to the degeneration of motor neurons in ALS. Expression of apelin, an endogenous ligand for the G protein-coupled receptor APJ ...Weaken Edwyns Hold On OxfordshireIt's the one where you have to weaken Eadwyn's hold on Oxenefordscire. AC Valhalla Weaken Edwyns hold on Oxfordshire: Chipping …. wife fucks anything Was diagnosed with slow progressing ALS 2 1/2 years ago, been symptomatic going on 6. Had to quit working in March. Depression destroyed my marriage so now I'm without my best friend, partner and kids. Really just now starting to struggle with the basics, getting dressed, using utensils, etc...but I still manage.ALS occurs throughout the world with no racial, ethnic or socioeconomic boundaries. 50% of patients with ALS live 3 to 5 years. 20% live 5 to 10 years, and 10% survive 10 years or more. The average life expectancy with ALS is 2-5 years. Sporadic ALS is the most common form and accounts for 90-95% of all cases of ALS.What is ALS? Amyotrophic lateral sclerosis (ALS) is a progressive, incurable neurodegenerative disease that leads to the irreversible degeneration of motor neurons. Motor … cisco 9800 ap not joining An experimental medication may slow the progression of amyotrophic lateral sclerosis, or ALS, researchers reported Wednesday. The research was supported in part by donations from the Ice...I now do a vigorous daily routine of “simpler” movements. Example: crawling forward & back on hands and knees or full-body sideways rolling. About atrophy. Anytime we skip workouts and let our muscles get weak it is “atrophy.”. I think you are noticing the diminishing of the size of muscles that you once had.It all started with foot drop on one side. She noticed a change in her gait, foot dragging a bit, and eventually enough to cause her to trip easily. That said, like the sidebar says, we can't diagnose anything and MANY "symptoms" can come from a variety of ailments, some not quite as deadly as ALS. Trust in your doctors. FranklyDear • 4 yr. agoHelp people and families living with ALS As the disease progresses & more support is needed, the average cost of ALS to a family is $150,000-$250,000. You can make a donation to help offset the financial burden. Donate today Symptoms as ALS progresses Difficulty breathing Coughing when eating or drinking Difficulty forming words or projecting voiceAs ALS progresses, most voluntary muscles become paralyzed. As the muscles of the mouth and throat, and those involved in breathing, become paralyzed, eating, speaking, and breathing is compromised. During this stage, eating and drinking are usually require a feeding tube. Breathing is assisted via a ventilator.Help people and families living with ALS As the disease progresses & more support is needed, the average cost of ALS to a family is $150,000-$250,000. You can make a donation to help offset the financial burden. Donate today Symptoms as ALS progresses Difficulty breathing Coughing when eating or drinking Difficulty forming words or projecting voice section 8 houses for rent 48219 ALS usually occurs in one of two main ways: limb (spinal) onset or bulbar onset. Limb Onset Symptoms start in your arms or legs. Also called spinal ALS, limb onset tends to worsen more slowly...This video is about people with ALS who have not only stopped the progression of this horrible disease but about others who have also reversed it. Richard Be... utility truck for sale los angeles Our results confirm that there are several valid predictors of one-year mortality rate in ALS even at time of diagnosis: age over 75 years, short interval between symptom onset and diagnosis (≤6 months), rapid decline of body weight before diagnosis (≥2 BMI units within 6 months) and advanced functional impairment (FRS≤ 30 points).Amyotrophic lateral sclerosis (ALS) more commonly referred to as Lou Gehrig’s disease, is a progressive and deadly disease. Many with ALS experience grief and many families of those affected endure the same. At present medical science has demonstrated great potential in finding a workable cure or efficacious therapy.Up to 15% of people with ALS develop symptoms of a second brain disorder called frontotemporal dementia (FTD). It is a progressive condition that affects personality, speech, and behavior.... sexy yoga chicks It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time.Jun 26, 2014 · The ALS Association Support Community connects patients, families, friends and caregivers for support and inspiration. This community is sponsored by the ALS Association, an Inspire trusted partner. Learn more Related posts Still waiting for a diagnosis - I’m certain it’s ALS 20 months from symptom onset. All the tests a human can endure. 11 ago 2022 ... Importantly, NDM was able to recapitulate the dynamics of pathological progression in ALS. Understanding the spatial shifts in the seeds of ... how tall is demetrius flenory Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neuron populations of the cerebral cortex, brainstem, and spinal cord, leading to progressive disability and death from respiratory failure. ALS is a highly heterogeneous disease demonstrating varied clinical phenotypes and rates of disease progression.Jan 26, 2008 #1 hello again. How fast does als progress? Within the past three weeks I have gone from feeling strong and perfectly healthy to having muscle weakness fasciculations, and cramps in my legs as well as weakness in my arms and cramps in my shoulders.I now do a vigorous daily routine of "simpler" movements. Example: crawling forward & back on hands and knees or full-body sideways rolling. About atrophy. Anytime we skip workouts and let our muscles get weak it is "atrophy.". I think you are noticing the diminishing of the size of muscles that you once had. fantasy maps generator Summary word count: 213. Introduction. Also known as ‘Lou Gehrig’s Disease’, Amyotrophic Lateral Sclerosis (ALS) involves loss of upper and lower motoneurones from the brainstem and …Adf [email protected] is on Instagram • 74. Simplify agile project processes and sprint plans with Asana. Java(sprint boot), Spark, Scala/Python, ADF, ADB, SQL, AWS Lambda, Kinesis Streaming 2. The mean ALSFRS-R score in the ALS cohort was 40.5 ± 0.3, indicating mild–moderate degree of functional disability. As expected, the ALSFRS-R score was … how to record ppp loan forgiveness on financial statements 14 mar 2018 ... Amyotrophic lateral sclerosis (ALS) — otherwise known as Lou Gehrig's disease or motor neuron disease — can kill someone within a few months of ...I can measure FVC, slow vital capacity (which many ALS doctors prefer) MIP (inspiratory strength) MEP (expiratory strength) MVV (the amount of air you can move in 12 seconds, and much more. Although my FVC is never normal, it varies by time of day. Best before food. Same lying down as sitting up. pj trailer ramps Most people who develop ALS are between the ages of 40 and 70, with an average age of 55 at the time of diagnosis. However, cases of the disease do occur in people in their twenties and thirties. ALS is 20% more common in men than women. However, with increasing age, the incidence of ALS is more equal between men and women.Jul 6, 2018. #1. Hello to everyone, this is my first post, after spending a lot of time browsing the forums. It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months ...Many people who have muscle twitching worry that they have ALS since it's often associated with the disease. If a person has muscle twitches a lot, ...why duke essay reddit Contextual translation of "apj abdul kalam quotes about education" from Danish into Albanian. Examples translated by humans: MyMemory, World's ... According to the ALS Association, half of all people affected with ALS live at least three or more years after diagnosis. Twenty percent live five years or more; up to 10 percent will live more... houses to rent tipton Introduction Adults with amyotrophic lateral sclerosis (ALS) have been using home mechanical ventilation for over 50 years. More recently, home respiratory care has evolved to include portable home ventilators, airway clearance devices, and physiological assessments with telemonitoring capability. Current State of Respiratory CareAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that is complex in its onset, pattern of spread, and disease progression. The heterogeneity of ALS makes it extremely challenging to determine if a disease modifying therapy is effectively slowing progression.Most people who develop ALS are between the ages of 40 and 70, with an average age of 55 at the time of diagnosis. However, cases of the disease do occur in people in their twenties and thirties. ALS is 20% more common in …Each occurrence of ALS is unique, and there is no clear-cut time frame for how an individual's disease will progress. For example, symptoms may appear gradually over time, or they may occur rapidly and then plateau. The stages and strategies outlined below offer a general idea of the physical progression of ALS, the types of assistance needed as symptoms worsen, and the role caregivers can ... wfbius6s tax id Answer (1 of 43): This was me as of October of 2017: Around December of 2017, I looked like this: Before I delve into specifics, let me give you my background. I’m of Asian ethnicity, Meso/Endomorph, and I’ve always been carrying some fat, so at my worst, I was skinny fat. I did calisthenics w...ALS is a progressive, fatal motoneurone disease, ultimately leading to paralysis and respiratory failure within 3-5 years. There is currently only one FDA-approved drug, Riluzole, but its lack of disease prolongation combined with the aggressive disease nature means identifying new treatments is essential.In general, the progression of ALS is rapid, and this would seem the case, being that the average survival at the time of diagnosis is just two to five years. When the initial onset occurs in the lower limbs, the progression of ALS tends to be slower than if the onset begins in the upper body. Lorra Garrick has been covering medical, fitness ... winport no deposit bonus codes Most people with ALS eventually lose the ability to walk, dress, write, speak, swallow and breathe, and their life span is shortened. Early symptoms of ALS often include muscle weakness or stiffness. Progression of weakness, wasting and paralysis of the muscles of the limbs, trunk, and those that control vital functions generally follows.Amyotrophic Lateral Sclerosis (ALS) Life Expectancy. The life expectancy for someone with amyotrophic lateral sclerosis (ALS) varies, but tends to range from two to five years. 1 Some people with ALS do live much longer, however. About 10% of those with the condition will live 10 years, and 5% will live for 20 or more years. 2. werewolf romance novels free download pdf Amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease, displays varying early symptoms such as tripping, dropping things, fatigue, slurred speech, muscle cramps, twitches, laughing and crying, states the ALS Association.In general, the progression of ALS is rapid, and this would seem the case, being that the average survival at the time of diagnosis is just two to five years. When the initial onset occurs in the lower limbs, the progression of ALS tends to be slower than if the onset begins in the upper body. Lorra Garrick has been covering medical, fitness ... powerbuilding program excelJul 6, 2018 · Jul 6, 2018. #1. Hello to everyone, this is my first post, after spending a lot of time browsing the forums. It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months ... Consequently, many patients with ALS tolerate NIV poorly and must face the harrowing decision of hospice vs tracheostomy. Advancement of respiratory care in ALS has been hindered by critical gaps in pulmonologist availability, training in chronic respiratory failure, financial support, clinical research, and clarity on ventilation management ... dinar recaps okie It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time.Minimal side effects were reported; the main one being burning sensation at the site of infusion. Currently, two drugs have been approved to slow the progression of ALS: riluzole (Rilutek), shown to increase life expectancy by three months, and edaravone (Radicava), shown to decrease decline of physical function by 33 percent at 24 weeks. blood plasma for money near me Share What is ALS?Amyotrophic lateral sclerosis (ALS) is a progressive, incurable neurodegenerative disease that leads to the irreversible degeneration of motor neurons. Motor …Weaken Edwyns Hold On OxfordshireIt's the one where you have to weaken Eadwyn's hold on Oxenefordscire. AC Valhalla Weaken Edwyns hold on Oxfordshire: Chipping ….In terms of reversal, there are 15 cases to date (maybe more my numbers may be outdated) where patients with a clinical diagnosis of ALS have reversed their symptoms. There is a great initiative called ALS Untangled that academically …The final stage of ALS occurs when the body becomes completely paralyzed. People in this stage can't breathe, speak, or swallow and require a ventilator and a feeding tube. During this stage, people with ALS are usually given hospice care and aren't expected to survive more than 6 months. 4. ALS is always fatal. off grid cabins for sale in the upper peninsula of michigan Dec 18, 2020 · Lisa, ALS is a family of diseases with widely different progression and start points. What one person experiences and does may not apply to you. Sadly, I’ve found the science lacking. I’ve had the talks with multiple PT’s and neurologists. Haven’t heard much more profound than don’t hurt yourself and don’t over tire yourself. “All slow the rate of the progression, but none of them stop the disease or reverse the symptoms,” Dr. Horak says. “The clinical trials definitely show that ...National Center for Biotechnology InformationAmyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. plumas county sheriff That's about the same number of Phase 2 or 3 ALS trials completed, terminated, or suspended from 2007 to 2018, Goyal calculated in a study in the journal Muscle & Nerve in January 2020. In that ...These history sections are still a work-in-progress, and may not yet contain changes relevant to the current version of the Calamity Mod. DCM is one of the most common organic solvents used in synthetic chemistry labs. If a slave escapes, then The Slave Owner, would detonate this bomb, making The Slave die a gruesome and torturous death. ...ALS’s assault on Gallegos’ central nervous system continued. He relied more on voice-to-text software for emails and text messages. His lung capacity diminished, requiring more time on a... samsung elite affiliation code t mobile 2 stroke outboard fuel consumption chart. desmume crashes when loading rom. sports afield safe battery dead no key; how to see hidden text in screenshot onlineMore than 3,000 people and families throughout Canada continue to face the profound emotional, financial, and psychological impact of living with ALS. Their collective experience is core to every action we take and decision we make. And every person affected by this devastating disease is reason enough for our […] winnebago county rental assistance These history sections are still a work-in-progress, and may not yet contain changes relevant to the current version of the Calamity Mod. DCM is one of the most common organic solvents used in synthetic chemistry labs. If a slave escapes, then The Slave Owner, would detonate this bomb, making The Slave die a gruesome and torturous death. ...Amyotrophic lateral sclerosis (ALS) more commonly referred to as Lou Gehrig's disease, is a progressive and deadly disease. Many with ALS experience grief and many families of those affected endure the same. At present medical science has demonstrated great potential in finding a workable cure or efficacious therapy.According to the ALS Association, half of all people affected with ALS live at least three or more years after diagnosis. Twenty percent live five years or more; up to 10 percent will live more...Early symptoms of ALS usually include muscle weakness or stiffness. Gradually all voluntary muscles are affected, and individuals lose their strength and the ability to speak, eat, move, … 22 inch chrome rims for ford f150 ALS usually occurs in one of two main ways: limb (spinal) onset or bulbar onset. Limb Onset Symptoms start in your arms or legs. Also called spinal ALS, limb onset tends to worsen more slowly... ALS is a progressive condition that is terminal within five years for 80% of the people impacted by it. ALS affects the nerves that control movement. As it progresses, people with ALS are unable to move their arms and legs to walk or get out of bed, and they eventually lose the ability to talk, eat, and breathe on their own. 3 How ALS Causes Death gay massage orlando In theory, "reversing" ALS in a pathophysiological sense would be regrowing the neurons that have degenerated or replacing them with new ones. Consequently, muscle health would also be regained as long as the upper and lower motor neurons are reinnervated.It seems like a very supportive place. I've noticed in these groups as well as in the local ALSA support group we go to, that some people are dealing with the stress and demands of a fairly rapid progression: that is, in 3 - 4 months, going from ambulatory to powered wheelchair. Big changes in a short time.Our objective was to develop: 1) a longitudinal model to describe amyotrophic lateral sclerosis (ALS) disease progression using the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R); and 2) a probabilistic model to estimate the presence of clusters of trajectories in ALS progression over 12 months of treatment.The progression of this disease seems to be so varied person to person. My father told me he had the disease fathers day June 2019. At that point the only symptom he had was drop foot … yandere genderbent disney x reader lemon Weaken Edwyns Hold On OxfordshireIt's the one where you have to weaken Eadwyn's hold on Oxenefordscire. AC Valhalla Weaken Edwyns hold on Oxfordshire: Chipping …. Progression. As ALS progresses, people living with the disease will find it more difficult to walk and move around, and they will eventually require support to do so. Their symptoms will …Feb 4, 2019 · Jacksonville Feb 4, 2019 #1 My mom’s FVC was 50% during her initial respiratory evaluation at the ALS Clinic at Mayo. Because of this, she is not a candidate for any clinical trials. She will be receiving a cough assist and trilogy. Does her diminished pulmonary function indicate ALS progression is aggressive? She is considered bulbar onset ALS. Many people who have muscle twitching worry that they have ALS since it's often associated with the disease. If a person has muscle twitches a lot, ... homes for sale in glen cove ny May 19, 2021 · Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that is complex in its onset, pattern of spread, and disease progression. The heterogeneity of ALS makes it extremely challenging to determine if a disease modifying therapy is effectively slowing progression. 1 Identifying Patterns of ALS Progression from Sparse Longitudinal Data Divya Ramamoorthy1, Kristen Severson2, Soumya Ghosh2, Karen Sachs1, Answer ALS, Jonathan D. Glass3, Christina N. Fournier3, Pooled Resource Open-Access ALS Clinical Trials Consortium*, James Berry4, Kenney Ng2, Ernest Fraenkel1 Abstract Amyotrophic Lateral …A small study reported in The Lancet on Friday indicates that a diet heavy in calories and carbohydrates may slow progression of Lou Gehrig's disease. Formally referred to as amyotrophic lateral... 8x170 dually wheels 22 14 feb 2018 ... My brother has slow progressing als. He was diagnosed on May of 2015, but had symptoms as early as the end of 2013. 2015 was mostly normal with ...25 ago 2020 ... Amyotrophic lateral sclerosis (ALS) is a progressive neurological disease. ... and is one of the tell-tale signs of disease progression. shimano curaro In order to create a standardized way to track ALS disease progression, researchers have developed a questionnaire, the Revised ALS Functional Rating Scale (ALSFRS-r). Author Jonathan Gang Published Nov 18, 2022 Share For many diseases, keeping track of progression and symptom severity is a relatively straightforward task.2 sept 2022 ... Emerging evidence has linked metabolic deficits to ALS progression and severity [1]. Specifically, abnormalities in lipid metabolism are ... pittman gm9434 Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that is complex in its onset, pattern of spread, and disease progression. The heterogeneity of ALS makes it extremely challenging to determine if a disease modifying therapy is effectively slowing progression.ALS usually occurs in one of two main ways: limb (spinal) onset or bulbar onset. Limb Onset Symptoms start in your arms or legs. Also called spinal ALS, limb onset tends to worsen more slowly... ALS is a heterogeneous disease that presents and progresses differently in every patient. Monitoring disease activity is important to assessing functional decline and understanding rate of progression, as this is the ultimate determinant of disease prognosis. Tools to Monitor ALS Progression Progressive weakness is a hallmark of ALS. turkish sofa set dubai